Twin U.S. studies unlock mystery of how HIV causes AIDS

A drug user gives blood sample for a HIV test inside a clinic in AthensBy Julie Steenhuysen CHICAGO (Reuters) – U.S. scientists have discovered the basic mechanisms that allow HIV to wipe out the body's immune system and cause AIDS, which could lead to new approaches to treatment and research for a cure for the disease that affects 35 million people around the world. Instead of actively killing immune system cells known as CD4 T cells, much of the damage done by HIV occurs when the virus tries to invade these cells and fails, triggering an innate immune response that causes the cells to self-destruct in a fiery kind of cell suicide known as pyroptosis. …



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