Tag Archives: pill

Taking anti-HIV pill as needed prevents infection

By Andrew M. Seaman (Reuters Health) – Taking an anti-HIV pill shortly before sex and for a few days afterward can help protect people against infection with the human immunodeficiency virus, according to researchers in France and Canada. In 2012, the U.S. Food and Drug Administration approved the pill, known as Truvada, for so-called pre-exposure prophylaxis (PrEP) against HIV, the virus that causes AIDS. Uninfected individuals who take Truvada every day can cut their risk of getting HIV during sex by more than 90 percent, according to the U.S. Centers for Disease Control and Prevention (CDC).
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HIV pill could cut infections in gay, bisexual men by a third

By Andrew M. Seaman (Reuters Health) – The rate of new HIV infections among gay and bisexual men could drop by up to a third over the next decade if enough eligible men take a drug that protects against the virus, researchers estimate. According to the U.S. Centers for Disease Control and Prevention, eligible gay and bisexual men meet any of three criteria: they have unprotected anal sex in a monogamous relationship with a partner not recently tested for HIV, or they have unprotected anal sex with a partner outside of a monogamous relationship or they have any anal sex with someone who is HIV positive.
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Anti-HIV pill may not be reaching those most at risk

By Andrew M. Seaman Only a small proportion of gay and bisexual men who could have taken a daily pill to reduce their risk of HIV actually did so in 2014, according to a new study. Furthermore, young gay and bisexual men and those of color, who are among the groups most at risk for infection with the human immunodeficiency virus (HIV), were less likely to be taking the medication than their older and white counterparts. Unequal use of the drug, called Truvada, may worsen the disparities between races in HIV rates, said lead author Henry Raymond, of the San Francisco Department of Public Health.
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Anti-HIV pill not cost effective among U.S. drug abusers

By Andrew M. Seaman (Reuters Health) – Providing anti-HIV pills to people who abuse injection drugs in the U.S. would reduce infections and save lives but end up costing the healthcare system billions of dollars a year, researchers say. The message for policymakers is that pre-exposure prophylaxis (PrEP) use among injection drug abusers is effective, but very costly, said study author Dr. Douglas Owens. Currently, the daily pill known as Truvada, manufactured by Gilead, is the only form of PrEP approved by the U.S. Food and Drug Administration.
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Research brings the male birth control pill a step closer

Researchers at the University of Minnesota College of Pharmacy made promising steps by tweaking existing experimental compounds.Researchers have been trying to design a male contraceptive pill for years. Although a hormonal birth control pill for men isn't likely to come to market anytime soon, American researchers have presented promising new findings in the domain at the 251st National Meeting & Exposition of the American Chemical Society. Scientists at the University of Minnesota College of Pharmacy have focused on developing a soluble compound that starts working quickly and doesn't reduce libido.



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Anti-HIV pill, taken as needed, prevents infection in gay men

By Gene Emery (Reuters Health) – The odds of getting HIV can be dramatically reduced by taking two pills prior to sex and two more after, according to a new study of 400 high-risk gay men and transgendered women published online by the New England Journal of Medicine in conjunction with World AIDS Day. The medication is Gilead’s Truvada, a combination of tenofovir and emtricitabine, approved by the U.S. Food and Drug Administration in 2012 to prevent HIV infections and intended to be given daily. The study suggests that may not be necessary, and the pills can be taken as needed.
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Pill protects against HIV in real-world settings

By Andrew M. Seaman (Reuters Health) – A once-a-day pill for preventing infection with the human immunodeficiency virus (HIV), the virus that causes AIDS, has been effective in clinical trials, and new research suggests that it works in the real world, too. In a study conducted at sexual health clinics, participants taking the pills for so-called preexposure prophylaxis, or PrEP, had only two new HIV infections, although their rates of other sexually transmitted infections and condomless sex remained high, researchers found. “There were a number of clinical trials that looked at PrEP and showed it to be safe and effective in that research setting, but there was little information on how PrEP would be implemented outside of those research trials,” said lead author Dr. Albert Liu, of the San Francisco Department of Public Health.
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Encouraging results from real-world users of HIV-prevention pill

To match feature AIDS PROTECTIONBy Andrew M. Seaman (Reuters Health) – A pill meant to prevent HIV infections in high-risk individuals appears to be working, according to two new studies. In one study, conducted in the San Francisco area, there were no new HIV infections among 657 people who took the daily pill Truvada. In the second study, people in the UK taking Truvada had a lower risk of being diagnosed with HIV.



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Gilead combo HIV pill matches Truvada efficacy but safer in trial

(Reuters) – Gilead Sciences Inc said on Wednesday its experimental fixed-dose combination treatment for HIV proved as effective in a late-stage study as the company’s widely used Truvada combo pill but with significantly less loss of bone mineral density and kidney function. The company has already sought U.S. and European marketing approval for the new combo pill nicknamed F/TAF, which is meant to be a safer replacement for Truvada, a cornerstone of HIV treatment that has been associated with slight declines in bone mineral density and kidney function. “The results of this and other recent trials demonstrate the potential of F/TAF to become a next-generation backbone” of treatment for HIV, the biotechnology company said in a release.
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Pill taken before, after sex may prevent HIV: study

Pill taken before, after sex may prevent HIV: studyAn HIV prevention pill taken by gay men before and after sex reduced the risk of virus transmission by 86 percent, according to the results of a clinical trial released Tuesday. Truvada contains HIV treatment drugs tenofovir and emtricitabine, and is made by Gilead Sciences in California. While the latest evidence on the technique known as pre-exposure prophylaxis, or PrEP, is not enough to change guidelines, it was welcomed as a novel approach to HIV prevention. The study "provides the first evidence that an event-driven regimen is effective among high-risk MSM (men who have sex with men) with frequent sex," said Jonathan Mermin, director of the US Centers for Disease Control and Prevention's National Center for HIV/AIDS.



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