WEDNESDAY, July 6 (HealthDay News) — Women, older people and minorities are under-represented in lung cancer drug trials in the United States, according to a new study.
Researchers say that this could have a significant impact on the efficacy and safety of new treatments among these groups, particularly the elderly.
“Our results suggest that the trial population used for approval of drugs do not represent well the U.S. population who may receive the marketed agent,” the study’s principal investigator, Dr. Shakun Malik, a medical officer at the U.S. Food and Drug Administration in Silver Spring, Md., said in a news release.
“This fact is concerning particularly for older patients who may experience greater toxicity when given the same dose and combination of drugs based on testing in a younger population,” Malik explained in the release from the International Association for the Study of Lung Cancer.
In conducting the study, which was slated for presentation Wednesday at the 14th World Conference on Lung Cancer in Amsterdam, researchers reviewed 10 years of trial data for the treatment of non-small cell lung cancer submitted to the U.S. Food and Drug Administration.
Continue reading “Patient Disparities Seen in Lung Cancer Drug Trials”
Tags: Cancer, Cancer Hospitals, lung cancer
The active compounds in green tea might slow the progression of prostate Cancer, the results of a small study suggest.
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Continue reading “Green Tea Component May Slow Prostate Cancer”
Tags: Cancer, green tea, prostate cancer
Lifestyle choices are pieces of the cancer prevention puzzle, but exactly which steps to take remain unclear, even to scientists. Still, more and more individuals are incorporating small changes into their daily routine such as drinking green tea in hopes of keeping cancer risk at bay.
Is it working? A large new Cochrane review of studies that examined the affect of green tea on cancer prevention has yielded conflicting results.
Researchers looked at 51 medium- to high-quality studies that included more than 1.6 million participants. The studies focused on the relationship between green tea consumption and a variety of cancers, including breast, lung, digestive tract, urological prostate, gynecological and oral cancers.
Continue reading “Green Tea: Mixed Reviews For Cancer Prevention”
Tags: Cancer, green tea
What is Mesothelioma? Bakersfield residents- Get all the information you need at our website. Mesothelioma is a disease, the only known cause of which is Asbestos exposure. …
Continue reading “Mesothelioma Cancer What is Mesothelioma? Bakersfield – Video”
Tags: Cancer, mesothelioma
Mesothelioma is a form of cancer that is almost always caused by exposure to asbestos. In this disease, malignant cells develop in the mesothelium, a protective lining that covers most of the body’s internal organs. Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the heart, the pericardium (a sac that surrounds the heart) or tunica vaginalis.
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases risk of other asbestos-induced cancer. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma (see asbestos and the law).
Continue reading “Mesothelioma Cancer”
Tags: Cancer, mesothelioma
Many decades ago, doctors had limited knowledge of mesothelioma cancer, most cases of the disease were seen by family doctors who had very little knowledge about the cancer, the symptoms and methods of treating the cancer.
Although this asbestos related cancer is rare in comparison to other more common types of cancer, there has been a gradual increase in the number of diagnosed cases over the past 20-30 years, some medical doctors have become specialist and experts in the diagnosis and treatment of this terrible disease.
Most times the first medical professional that a mesothelioma patient will have contact with will be their family physician. The family physician will order for several imaging tests once there is reasonable clinical suspicion, to be able to make definitive diagnosis. Once a definitive diagnosis is made, the family physician will refer the patient to an oncologist, who may be located in the area where the patient lives.
Continue reading “Mesothelioma Doctors – How Do You Find The Best One For You?”
Tags: Cancer, mesothelioma
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that can detect cancer more effectively.
“Tumor cells sometimes shed proteins into a patient’s bloodstream,” said VARI Senior Scientific Investigator Brian Haab, Ph.D., whose lab published its findings in the journal Molecular & Cellular Proteomics. “These proteins can have carbohydrate structures attached to them that might be able to tell us not only if a patient has cancer, but also more about the cancer and how to treat it.”
Continue reading “New Tool May Help With Early Detection Of Deadly Pancreatic Cancer”
Tags: Cancer, pancreatic cancer
Metformin, one of the most widely used diabetes drugs, may offer patients the added benefit of lowering their odds for pancreatic cancer by 60 percent, a new study shows.
But the study had a downside: Other common treatments, including the use of insulin or insulin-releasing medications such as sulfonylureas, seemed to boost diabetics’ risk for the deadly malignancy.
Continue reading “Metformin May Lower Diabetics’ Odds for Pancreatic Cancer”
Tags: Cancer, cancer treatment, metformin, pancreatic cancer
Immune systems
The immune systems of AIDS are primarily the result of conditions that do not normally develop in individuals with healthy immune systems. Most of these conditions are infections caused by bacteria, viruses, fungi and parasites that are normally controlled by the elements of the immune system that HIV damages.
Opportunistic infections are common in people with AIDS. HIV affects nearly every organ system.
People with AIDS also have an increased risk of developing various cancers such as Kaposi’s sarcoma, cervical cancer and cancers of the immune system known as lymphomas. Additionally, people with AIDS often have systemic immune systems of infection like fevers, sweats (particularly at night), swollen glands, chills, weakness, and weight loss. The specific opportunistic infections that AIDS patients develop depend in part on the prevalence of these infections in the geographic area in which the patient lives.
Continue reading “AIDS Symptoms”
Tags: AIDS, AIDS symptoms, Cancer, HIV, pneumocystis pneumonia, tumor
The first challenge is that testicular cancer is rare and therefore limits the number of cases for analysis in any but the largest prospective studies. While the obvious solution to the problem of rare diseases is to conduct a case-control study, in the case of testicular cancer prospective data may be more important than the convenience of easily available cases.
Testicular cancer incidence appears to be increasing worldwide. Despite growing concern over this increase, many aspects of testicular cancer epidemiology remain puzzling. So far, science provides few answers for its etiology or the geographic and temporal discrepancies in its incidence. Unfortunately, further evidence about the causal factors for testicular cancer will not be quickly forthcoming.
Continue reading “Maternal Drinking And Son’s Testicular Cancer: The Next Step”
Tags: Cancer, testicular cancer
