Category Archives: Pharmacy & Pills

Patient Disparities Seen in Lung Cancer Drug Trials

WEDNESDAY, July 6 (HealthDay News) — Women, older people and minorities are under-represented in lung cancer drug trials in the United States, according to a new study.

Researchers say that this could have a significant impact on the efficacy and safety of new treatments among these groups, particularly the elderly.

“Our results suggest that the trial population used for approval of drugs do not represent well the U.S. population who may receive the marketed agent,” the study’s principal investigator, Dr. Shakun Malik, a medical officer at the U.S. Food and Drug Administration in Silver Spring, Md., said in a news release.

“This fact is concerning particularly for older patients who may experience greater toxicity when given the same dose and combination of drugs based on testing in a younger population,” Malik explained in the release from the International Association for the Study of Lung Cancer.

In conducting the study, which was slated for presentation Wednesday at the 14th World Conference on Lung Cancer in Amsterdam, researchers reviewed 10 years of trial data for the treatment of non-small cell lung cancer submitted to the U.S. Food and Drug Administration.


Therapeutic actions: Trachisan is a combined synthetic preparation, which includes a topical antibiotic called Tyrothrycin, and antiseptic chlorhexidine and anesthetic lidocaine. This combination of components exerts anti-inflammatory, antimicrobial and pain relieving action. The preparation is effective against a wide variety of bacterial strains, fungi (Candida albicans) and viruses. The drug is used for local treatment only.

Indications: Trachisan is indicated in treatment of the following conditions:

  • Infectious disease of the oral cavity and throat
  • Stomatitis
  • Ghingivitis
  • Paradontitis
  • Glossitis
  • Tonsilitis
  • Pharingitis
  • Prophylaxis before oral surgery

Sometimes the drug is also prescribed as additional therapy with systemic antibiotics and etc.

Tabex – treatment of tobacco smoking


Tabex - treatment of tobacco smoking

Tabex is an original Bulgarian preparation of plant origin, intended for the treatment of tobacco smoking. The preparation is developed on the basis of the alkaloid Cytisine, contained in the plant Cytisus laborinum L. (Golden Rain acacia). In the human body, Cytisine plays the role of nicotine substitution substance, and reduces the period of interction of the received nicotine with relevant nicotine receptors, i.e. the specific substance cytisine “substitutes” nicotine, acting on the same receptors, thus preventing the appearance of abstinence syndrome. This results in a gradual reduction and suspension of the psychic and physical dependency to nicotine in smokers.

Indications: Smoking cessation in smokers.

Protein in Beef

Protein in Beef

Protein in Beef

Protein is a critical nutrient in all beef cattle diets. Although protein supplementation is often a high cost item in beef cattle feeding program, sometimes protein supplementation is needed to meet the animal’s nutrient requirements.

Signs of protein deficiency include lowered appetite, weight loss, poor growth, depressed reproductive performance, and reduced milk production.

Providing adequate protein in beef cattle diets is important for animal health and productivity as well as ranch profitability.

Abortion pill approved in Italy

Italy’s drug regulation agency has approved the use of the abortion pill RU486, also known as mifepristone, prompting protests from the Vatican.

The Italian Pharmaceuticals Agency (AIFA) ruled late on Thursday that the drug would not be sold in pharmacies and only be administered by doctors.

The pill could only be taken up to the seventh week of pregnancy, it said.

On Thursday, the Vatican said it would excommunicate doctors who prescribed the drug and patients who used it.

Metformin May Lower Diabetics’ Odds for Pancreatic Cancer

Metformin May Lower Diabetics' Odds for Pancreatic Cancer

Metformin, one of the most widely used diabetes drugs, may offer patients the added benefit of lowering their odds for pancreatic Cancer by 60 percent, a new study shows.

But the study had a downside: Other common treatments, including the use of insulin or insulin-releasing medications such as sulfonylureas, seemed to boost diabetics’ risk for the deadly malignancy.

“We have been long interested in the association between diabetes and pancreatic Cancer,” explained study lead author Donghui Li, a professor in the department of gastrointestinal medical oncology at the University of Texas M.D. Anderson Cancer Center in Houston. “It’s a very complicated association because pancreatic Cancer can cause diabetes, while on the other hand diabetics have a higher risk for pancreatic Cancer. So it’s been quite controversial, and the question is: What can we do to reduce this risk?”

South Africa launches new AIDS research

new AIDS research

South Africa launched a new HIV/AIDS research initiative Tuesday aimed at stimulating scientific studies into the prevention, diagnosis and treatment of the disease.

South Africa had about 5.2 million people living with HIV last year  the highest number of any country in the world. The government is under pressure to show its commitment to combat AIDS after years of official denial, neglect and unscientific responses that fueled the world’s worst AIDS crisis.

The South Africa HIV/AIDS Research and Innovation Platform (SHARP) aims to back research including studies on new or improved treatments, drug design, gene research and vaccines.

Wal-Mart weighs role in U.S. H1N1 vaccination plans

H1N1 vaccination plans

Wal-Mart weighs role in U.S. H1N1 vaccination plans

Wal-Mart Stores Inc is discussing with U.S. health officials the possibility of putting vaccination sites at some of its stores for an H1N1 swine flu inoculation campaign this fall, a company official said on Thursday.

Federal officials met with Wal-Mart executives on Wednesday in Arkansas to discuss the issue, Dr. John Agwunobi, president of health and wellness for Wal-Mart U.S., told public health leaders at a conference in Orlando.

“We are in discussions with CDC (U.S. Centers for Disease Control and Prevention) and others in local and state departments to see what role we might play,” Agwunobi said. “It might be we are a site. It may be help with logistics and with supply chain.”

New tests aid drug performance

New tests aid drug performance

Better diagnostic tests and pressure to lower healthcare costs may finally usher in the era of personalized medicine, in which patients get drugs tailored to their genetic makeup, a new report suggests.

Personalized medicine has been a researcher’s dream since 2003 when scientists completed the Human Genome Project – a decade-long race to sequence all of the DNA in people.

Drug companies and regulators are now looking for tests that increase the odds a high-cost biotechnology drug will work. They are using biomarkers – such as specific proteins or genes – to design better and cheaper clinical trials, lowering the cost of drug development.

RU-486 abortion drug to be allowed in Italy

abortion, RU-486, abortion drug,  abortion drug RU-486, contraception, pregnancy

RU-486 abortion drug

Italy has approved the use of the abortion drug RU-486, capping years of debate and defying opposition from the Vatican, which warned of immediate excommunication for doctors prescribing the pill and for women who use it.

The pill is already available in a number of other European countries. Its approval by Italy’s drug regulation authorities was praised by women’s groups and pro-choice organizations, which say the pill will provide women with an additional, noninvasive procedure.

It drew the immediate protest of the Catholic Church, which opposes abortion and contraception.

“That’s not how you alleviate human suffering, that’s not how you help women, that’s not how you help mankind,” Monsignor Elio Sgreccia, a senior church bioethicist, said in an interview Friday with Associated Press Television News.